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© 2019 Indian Journal of Otology | Published by Wolters Kluwer - Medknow90AbstractOriginal ArticleintroduCtionMultiple sclerosis (MS) is a chronic inflammatory demyelinating disease affecting the central nervous system (CNS). Disseminated neurological symptoms caused by acute and chronic inflammation include loss or alteration of sensation (numbness, paresthesia), of motor function (typically spastic paresis or complete paralysis), visual symptom such as blurring of vision, transient blindness, disorder of conjugate eye movements, bladder, bowel dysfunction, and cognitive impairment. MS patients require enduring medical and rehabilitative care. Fatigue is one of the most common symptoms reported by patients with MS, which is reported to affect between 50% and 80% of patients.[1]The diagnosis of MS is based on representing evidence of inflammatory-demyelinating harm within the CNS that is disseminated in both time and space. Diagnosis is through a combination of the clinical history, neurologic examination, magnetic resonance imaging, and the exclusion of other diagnostic possibilities. Other so-called “para-clinical” tests, including the examination of the cerebrospinal fluid, the usage of evoked potentials, urodynamic studies of bladder function, and ocular coherence tomography, may be helpful in forming the diagnosis of MS, but are often unnecessary.[2]MS is characterized by episodes (“attacks” or “relapses”) of neurologic dysfunction. The symptoms caused by these attacks vary significantly between patients and depend on the site of neurologic involvement. Commonly, patients may complain of numbness, tingling, weakness, vision loss, gait impairment, incoordination, imbalance, and bladder dysfunction. Between these attacks, in the relapsing-remitting (RR) phase of the illness, patients are neurologically stable.[3]Many patients who begin with RRMS progress to the secondary progressive phase of the illness, in which they have marked worsening of function and increasing of neurologic disability not related to any acute attacks that may or may not occur. About 66% of RRMS patients developed SPMS at an average time of 15 years,[4] while in a British Columbia cohort study, 58% of patients with relapsing MS advanced to SPMS after an average time of 19.1 years.[5]Objectives: To evaluate central auditory functions in multiple sclerosis (MS) patients. Subjects and Methods: Twenty Egyptian MS patients involved in the study and 20 healthy controls who were matched to MS group in age, gender, and literacy. They ranged in age from 30 to 50 years with a mean age 37.6 ± 5 in the study group versus 37.3 ± 4.2 in the control group. In this study, four screening tests were conducted for the assessment of central auditory processing: Gaps In Noise test (GIN), Arabic dichotic digits test (DDT), Pitch Pattern Sequence test (PPS), and last Arabic Speech In Noise test (SPIN). Results: The study showed elevated GIN test approximate threshold and depressed total score in MS patients compared to the control group, with no significant difference between both right and left ears. There was statistical significant depressed scores in study groups at PPS, speech intelligibility in noise, and DDTs. Conclusion: The findings of the current study add more evidence to the involvement of central auditory processing abilities in patients with MS. The assessment of central auditory function is highly recommended for all MS patients as a routine examination and can be used for monitoring the effectiveness of medication and related therapies for these patients
ABSTRACT: Background: Interstitial lung diseases (ILD) are a group of diffuse parenchymal lung disorders associated with cough, dyspnea, hypoxemia and restrictive pulmonary function. Vertigo and dizziness are early symptoms of cerebral hypoxia Aim: The aim of this study was to assess the effect of hypoxia and chronic cough in patients with ILD on central and peripheral vestibular functions. Method: A cross sectional study was conducted in Audio-vestibular unit, ENT Department and Chest Department, Zagazig University Hospitals. Sixty two patients diagnosed to have ILD were included. Full VNG test battery was done. Results: There was statistical significance decrease in mean of optokinetic speed and smooth pursuit gain at high frequency (0.6) in both Rt & LT sides among cases who had moderate hypoxia compared to cases who had mild hypoxia). No difference was found between mild and moderate cases in other oculomotor tests parameters. Also, there was statistical significance increase in frequency of BPPV among cases who had moderate hypoxia compared to cases who had mild hypoxia.
ABSTRACTBackground:Cochlear implant (CI) is a hearing device that helps hearing impaired childrenwho did not benefit from conventional hearing aids to restore a satisfactory level of auditorysensation. The proper verification of their auditory speech and language performance helps gainthe best outcomes. Speech perception tests are basic assessment tools. They are considered assupra-threshold tests that use different speech materials that are reliable for hearingimpaired children.Objectives:The aim of this study is to assess the correlation between the different speech per-ception tests and auditory skills, language acquisition and speech parameters for cases with CIchildren in Zagazig University Hospitals. This will help develop an appropriate battery for verifi-cation of CI children.Design:This study was applied on 21 children with CI who had implanted before the data col-lection period. For all participants aided thresholds, APAL, WIPI and PBKG tests were done inthe audio-vestibular medicine unit for assessment of audiological outcomes. Assessment of audi-tory skills, language acquisition and speech parameters were done in the Phoniatric Unit. Theresults were collected and statistically analyzed.Results:There was a strong positive correlation between APAL and TLA, auditory skills andintelligibility of speech, which was superior to other speech perception tests.Conclusion:APAL can be used as a reliable speech discrimination test that can anticipate theprogress in different skills of pre-lingual CI children.
AbstractPurposeBehavioral evaluation of language development is an important index for the usefulness of cochlear implantation. However, it could not apply to infants and very young children. It is useful to adopt an objective measure to examine speech discrimination in this population. Thus, the current study aimed to predict the different behavioral language performance (good versus poor) in cochlear implant (CI) recipients through the auditory cortical assessment of speech discrimination with mismatch negativity (MMN).MethodsThe study comprised 40 CI children who were divided into two groups according to their behavioral language evaluation outcomes: 20 good and 20 poor CI performers. They were age, gender, and socioeconomically matched. The MMN was examined and compared between both groups with finding out the relationship between MMN and different variables.ResultsMMN existed in all good performers and 87.5% of the poor performers. There were significantly shorter latency, larger amplitude, and a larger area of MMN in the good performers. The MMN results correlated with a significant predic-tive effect on the behavioral measures of language evaluation.ConclusionThe MMN is a clinically applicable objective measure of speech discrimination proficiency. Hence, it could be useful in CI programming and auditory cortical monitoring during rehabilitation.Keyword Cochlear implantation · Auditory cortical processing ·
FINDINGS OFVIDEO HEAD IMPULSE TEST IN VESTIBULAR NEURITISSara Omar El farouk Zaiton1,Soha Abdelraouf Mekki1,Walid Mohamed Ibraheem1 andNahlaHassan Gad11Audio-vestibular unit, Department of ENT, Faculty of Medicine, Zagazig University,Zagazig, EgyptCorresponding author:Dr. Sara Omar El farouk ZaitounFaculty of Medicine,Department of ENT,Zagazig University, Zagazig, EgyptTel:01116764330E–Mail:Ziton8080@gmail.comAbstractBackground: The video head impulse test (vHIT) assesses the vestibulo-occular reflex(VOR) by using a video-assisted examination of the impulsive maneuver. We studied theresults vHIT in vestibular neuritis patients.Subjects and methods: Acase control study was conducted inAudio-vestibular unit,Department of ENT, Zagazig University Hospitals. 24 patients with vestibular neuritis wereincluded. vHIT was done.Results: We calculated gain, gain asymmetry in the study group and compare the results withcontrol group.Conclusion:vHIT is the only test that assesses all sixsemicircular canals independently andwith a physiologicalstimulus, similar to how the patient uses the vestibular ocular reflexsystem in daily life.Keywords:vestibular neuritis, vHIT.INTRODUCTI
Objectives: To evaluate central auditory functions in multiple sclerosis (MS) patients. Subjects and Methods: Twenty Egyptian MS patients involved in the study and 20 healthy controls who were matched to MS group in age, gender, and literacy. They ranged in age from 30 to 50 years with a mean age 37.6 ± 5 in the study group versus 37.3 ± 4.2 in the control group. In this study, four screening tests were conducted for the assessment of central auditory processing: Gaps In Noise test (GIN), Arabic dichotic digits test (DDT), Pitch Pattern Sequence test (PPS), and last Arabic Speech In Noise test (SPIN). Results: The study showed elevated GIN test approximate threshold and depressed total score in MS patients compared to the control group, with no significant difference between both right and left ears. There was statistical significant depressed scores in study groups at PPS, speech intelligibility in noise, and DDTs. Conclusion: The findings of the current study add more evidence to the involvement of central auditory processing abilities in patients with MS. The assessment of central auditory function is highly recommended for all MS patients as a routine examination and can be used for monitoring the effectiveness of medication and related therapies for these patients
temporal processing disorders
الابحاث العلمية
1 -
Videonystagmography in patients with interstitial lung diseases (2021).
2 -
Auditory cortical processing in cochlear implanted children with different language outcomes (2020).
3 -
Caloric test versus video head impulse test in vestibular neuritis patients (2020).
4 -
FINDINGS OF VIDEO HEAD IMPULSE TEST IN VESTIBULAR NEURITIS (2019).
5 -
Central Auditory Function in Multiple Sclerosis Patients (2019).
6 -
gaps in noise test versus auditory fusion in diagnosis of auditory temporal processing disorders (2009).
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